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MEDWATCH: Epzicom® (Abacavir and Lamivudine)
By Stuart Katsh, MS,
RD
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(Return
to page 12) |
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Adverse
Reactions (continued)
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Lactic acidosis with increased
liver size.
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Epzicom can worsen Hepatitis
B infection.
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Lipodystrophy (lipoatrophy:
decreased fat in legs, arms, face and buttocks and lipoaccumulation: increased
{brown} fat on the upper back, in the abdomen and sometimes chest {gynecomastia}).
While Lipodystrophy has been seen when lamivudine and abacavir were used
as part of combination regimens, it is believed that lamivudine and abacavir
contribute very little to the fat redistribution.
-
Other side effects can include
abnormal dreams, anorexia, anxiety, cough, chills, diarrhea, dizziness,
dyspnea, fatigue, headaches, mild nausea, muscle aches, stomach pain,
tachycardia, and vomiting.
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Contraindications
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Hypersensitivity reaction
or serious allergic reaction to abacavir. If a reaction occurs, patients
must stop taking the medication immediately and not restart it without
their doctor’s approval.
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Liver problems or hepatitis
B infection.
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Pregnancy or breastfeeding
patients or patients planning to be pregnant.
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Drug-Drug
Interactions
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Patients must tell their
doctor if they are taking methadone, Hivid® (zalcitabine, ddC), Epivir
or Epivir-HBV® (lamivudine, 3TC), Ziagen (abacavir), Combivir®
(lamivudine and zidovudine) or Trizivir (abacavir, lamivudine and zidovudine).
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Copyright 2005 HIV ReSources,
Inc. Sharing this newsletter in any form with non-subscribers is strictly
prohibited. Library/Institution subscribers are permitted to share HIV
Nutrition Update html newsletter pages with up to five (5) employees or
volunteers. NO other redistribution allowed.
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Please Help To Keep
This Page Updated By Notifying
The Webmaster
If You Find A Link That's Outdated!
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HIV ReSources, Inc.
PO Box 39385
Fort Lauderdale, FL
33339-9385
USA
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© 2005
HIV ReSources, Inc.
Any use of the
information presented herein is done strictly at your own risk.
No responsibility
is implied or intended on the part of HIV ReSources Inc,
the editor,
or the publisher. Information on this site should not
be construed
as an endorsement of any kind.
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2/15/2005
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