• Issue Highlights
    • Conjugated Linoleic Acid In HIV/AIDS
    • Lexiva
    • Update Central - Vitamin Supplements
    Volume 8, Issue 6
    May/June 2004
    Examining the Role for Conjugated Linoleic Acid in HIV/AIDS - Part II: 
    Clinical Intervention Trials
    John Babish, Ph.D., is a molecular biologist who served as a tenured Associate Professor of Pharmacology and Toxicology at Cornell University for 17 years. He has authored or co-authored over one hundred peer-reviewed scientific articles, eight position papers, and two book chapters. The inventor of 14 U.S. and world patents, Dr. Babish is the Chairperson of Bionexus® Ltd. located in Ithaca, New York, the makers of NutriVir®. 




    HUMAN INTERVENTION STUDIES WITH CLA

    As reviewed in Part I of this article, there is strong evidence that feeding mixed isomers of Conjugated Linoleic Acid (CLA) decreases obesity and fat mass in numerous animal models. Replicating these animal results in clinical intervention studies has been inconsistent and the data are conflicting. (1) 
     


     
     

    Editors’ Note

    This issue highlights original research on clinical intervention trials using conjugated linoleic acid (CLA), N-acetylcysteine, and a patented organic form of chromium in HIV patients  with antiretroviral therapy-associated lipodystrophy. Patients in this phase I study will help researchers to make a preliminary assessment of the tolerability, safety and efficacy of BION493, the dietary supplement noted above. Patients interested in participating in the study may contact the Research Coordinator, Alan Lee at 212/229-2298 or AlanLeeRD@yahoo.com.

    In this issue the Medwatch column reviews information on Lexiva (fosamprenavir calcium), a prodrug of Agenerase (generic name, amprenavir. The Update Central column offers information on vitamins. We highlight the need for them, detrimental effects and issues related to research  efforts.

     
     
    Inside this issue:
    Feature   1
    Editors' Note   1
    Update Central 11
    Med Watch 17
    Resource Corner 19
    Publisher's Corner 20
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    6/1/2004