|
(Continued
from page 2)
|
|
|
|
Dry mouth immediately
causes loss of taste sensation. Long term dry mouth can cause dental caries
and loss of teeth, gum disease, stomatitis and glossitis, as well as nutritional
imbalance and undesired weight loss.
Gastrointestinal Effects:
Gastrointestinal irritation and ulceration is a serious problem with many
drugs such as antineoplastics used to treat Kaposi’s sarcoma, for example
vinblastine (Velban). The anti-osteoporosis drug alendronate (Fosamax)
is contraindicated in those patients who are unable to sit upright for
at least 30 minutes after taking it due to the danger of esophagitis. NSAIDs
such as ibuprofen (Advil, Motrin) or aspirin are known to cause stomach
irritation, dyspepsia, gastritis, ulceration and sudden, serious gastric
bleeding, sometimes leading to fatalities (Table 4).
|
|
|
|
|
TABLE
4. EXAMPLES OF DRUGS THAT CAN CAUSE GI BLEEDING/ ULCERATION
|
| Antineoplastics |
Aldesleukin Interleukin-2 (Proleukin) |
Fluorouracil (5-Fu) (Adrucil) |
Imatinib Mesylate (Gleevec) |
|
Leuprolide Acetate (Lupron) |
Mitoxantrone (Novantrone) |
|
|
|
Vinblastine Sulfate (Velban) |
Methotrexate (Methotrexate,
Rheumatrex) |
| NSAID, Analgesic, Antiarthritic |
Aspirin/ Acetylsalicylic Acid
(Bufferin, Ecotrin) |
Celecoxib (Celebrex) |
Diclofenac Sodium (Cataflam,
Voltaren) |
|
Etodolac (Lodine) |
Ibuprofen (Advil, Motrin) |
Indomethacin (Indocin) |
|
Ketoprofen (Orudis) |
Meloxicam (Mobic) |
Nabumetone (Relafen) |
|
Rofexib (Vioxx) |
Sulindac (Clinoril) |
Naproxen (Naprosyn, Anaprox,
Aleve) |
| Immunosuppresant |
Corticosteroids (Prednisone) |
|
Myophenolate Mofetil (Cellcept)
|
| Antiinfective |
Amphotericin B (Abelcet, Ambisome,
Amphotec, Fungizone) |
Ganciclovir Sodium (Cytovene) |
| Bisphosponates |
Alendronate (Fosamax) |
Risedronate (Actonel) |
|
| Miscellaneous |
Bromocriptine (Parlodel) |
Donepezil (Aricept) |
|
|
Trazodone Hcl (Desyrel) |
Levodopa (Dopar) |
|
|
|
|
|
Antineoplastic drugs often
cause severe nausea and vomiting. Severe, prolonged nausea and vomiting,
lasting as long as a week, have been reported with cisplatin (Platinol-AQ).
Dehydration and electrolyte imbalances are of immediate concern. Weight
loss and malnutrition are common long-term effects of these drugs, although
it is often difficult to distinguish these effects from the complications
of the disease itself.
| No
part of this newsletter may be reproduced in any form without permission
from the publisher. Copyright 2002 HIV ReSources, Inc. Email: subscriptions@hivresources.com |
|
|
| |
| |
|
Copyright 2002 HIV ReSources,
Inc. Sharing this newsletter in any form with non-subscribers is strictly
prohibited. Library/Institution subscribers are permitted to share HIV
Nutrition Update html newsletter pages with up to five (5) employees or
volunteers. NO other redistribution allowed.
|
| |
Please Help To Keep
This Page Updated By Notifying
The Webmaster
If You Find A Link That's Outdated!
|
| |
HIV ReSources, Inc.
PO Box 39385
Fort Lauderdale, FL
33339-9385
USA
|
| |
© 2002
HIV ReSources, Inc.
Any use of the
information presented herein is done strictly at your own risk. No responsibility
is implied or intended on the part of HIV ReSources Inc, the editor, or
the publisher. Information on this site should not be construed as an endorsement
of any kind.
|
| |
|
12/1/2002
|
|
|
|
|
