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Adverse
Reactions: Digestive System: most common- nausea and
diarrhea; less common- abdominal distention or pain, anorexia, aphthous
stomatitis, colitis, constipation, decreased appetite, diverticulitis,
duodenitis, dry mouth, dyspepsia, dysphagia, enteritis, esophagitis, flatulence,
gagging, gastritis, gastroesophageal reflux, gastrointestinal bleeding,
gastrointestinal disorder, increased appetite, increased thirst, mouth
sores, pancreatitis, stomatitis and vomiting.
Metabolic
and Nutritional Disorders: most common- increased liver function
tests; less common- peripheral edema, and body weight increase or decrease.
Contraindications:
clinically significant hypersensitivity to any of the components of the
formulation.
Nutrient-Herb-Drug
Interactions: Based on scientific studies of agents from the same pharmacologic
class, delavirdine may deplete carnitine, copper, vitamin B12 and zinc.
Patients should also avoid the use of St. John's Wort to limit possible
herb-drug interactions. |
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