HIV ReSource Review


PDF Access To Full HIV ReSource Review Issues And 
Abstracts Of Featured Alternative Articles
Issues 14-26
Alpha Lipoic Acid-Full Issue Black Seed
Botanical Use: Part 1- Full Issue Botanical Use: Part 2-Full Issue
Cannabis - Advocates Response
-Full Issue
Cannabis- Medical Use
DMSO-Full Issue Garlic-Full Issue
Glutamine HMB (beta-hydroxy-beta-
methylbutyrate)-Full Issue
Milk Thistle (Silymarin) Nitazoxanide (NTZ)-Full Issue
Zinc-Full Issue  

 
Issue 26
This issue is free in PDF
 A Review Of DMSO
By Sharon Ann Meyer, AA, AS, DTR
Sharon Ann Meyer, AS, AA, DTR, Certified HIV Counselor is the President of HIV ReSources, Inc., and Editor-In-Chief of the HIV ReSource Review.
 

The popularity of Dimethyl sulfoxide (DMSO) is evidenced in archives of several electronic lists that hold messages about its use. Athletes provide a wealth of anecdotal evidence that this compound helps to ease their aches and pains. Suspended football player Frank Wycheck's use of DMSO brought attention to the questionable treatment among mainstream U.S. audiences in 1994. Also know as Methyl sulfoxide, Sulfinylbis[Methane] and Me2SO, DMSO is a hazardous industrial solvent similar to turpentine that was originally a byproduct of the paper pulp manufacturing process.

This literature review  discusses the research on DMSO as of September 2000
and the reasons why people living with HIV may use it.

Issue 25 
 Nigella Sativa (Black Seed)
By Rachel Stern, MS, RD, CNS
Rachel Stern, MS, RD, CNS is a nutritionist for the North Jersey Community Research Initiative in Newark, NJ. She has also worked at the Women's Infectious Disease Clinic at the University of Medicine and Dentistry of NJ. Other experience includes positions at WIC, Head Start, Blue Cross/Blue Shield of New Jersey, Columbia University Institute of Reproduction, Research Corporation, and University of Wisconsin Department of Pediatrics.
 
Black seed or Nigella sativa may be used in foods, or as a therapeutic agent. Supplements are capsules of the ground seed, often mixed with other herbs. Published studies on its pharmacological activity are few and limited to in vitro or small animals. Very preliminary evidence is suggestive of a hepato-protective effect. It may also have use as an immune-enhancer or a chemotherapy adjuvant, but again, evidence is very limited and preliminary.

This article reviews the research on
Black seed or Nigella sativa as of July 2000.

  Issue 24
This issue is free in PDF
 Cannabis Advocates Response
Al Bryne and Mary Lynn Mathre, RN, MSN, CARN
Al and Mary Lynn are cofounders of Patients Out of Time a non-profit organization formed to lobby for patient access to therapeutic use of marijuana. The Patients Out of Time Web Site contains research data, historical records, legal cases, legislation, and position papers by organizations relating to the topic of medical Cannabis.
 

The authors of this article note information that they feel might be useful for those living with HIV and AIDS. The article notes common uses of Cannabis and relates information about patients in the Compassionate Investigational Drug Program for marijuana. We publish the authors viewpoint in accordance with our policy to print information submitted by others to discuss, refute, or challenge items identified in previously published Review articles. The views expressed in this article are those of the authors and do not reflect the policies or official positions of HIV ReSources Inc., the editors, authors, or the publisher. Please refer to the objective literature review of marijuana noted in our March/April 2000 issue. 
Issue 23
Use Of Therapeutic Marijuana
By Sharon Ann Meyer, AA, AS, DTR
Sharon Ann Meyer, AS, AA, DTR, Certified HIV Counselor is the President of HIV ReSources, Inc., and Editor-In-Chief of the HIV ReSource Review.
 

Numerous people believe the illegal status of marijuana jeopardizes the health of Americans by denying them access to a safe and effective medicine. An estimated 20 to 80 million Americans regularly smoke the herb. Too few consider both known and suspected risks of marijuana use. There is an enormous amount of science based information about this substance. We know it is widely used by certain patient groups despite the legal, social, and health problems associated with its use. Many of those living with HIV or AIDS use it for a variety of reasons. In one project, 71% of HIV-positive patients reported using marijuana.  Another study disclosed that patients used the substance as an adjunct to prescription medication treatments.  Reliable information on the potential risks and benefits of this controversial herb will help people to make educated treatment decisions.

This article reviews the research and use of marijuana as of March 2000 highlighting benefits and risks for users.

   Issue 22
This issue is free in PDF
Botanical Use Among People With HIV: Part 2
Nancy Spaulding-Albright RD, CNSD, LD/N
and Sharon Ann Meyer, AA, AS, DTR
Nancy Spaulding-Albright RD, CNSD, LD/N is an Outpatient Nutritionist in Sunrise, FL. She is the author of herbal articles in the Newsletter of the Oncology Nutrition Dietetic Practice Group, the Journal of the American Dietetic Association and Student DOCTOR. Nancy's goal to educate people on complementary issues assists health professionals, patients and clients to make informed decisions. This helps to protect health and wallets by bridging the gap that remains between conventional and complementary medicine. Sharon Ann Meyer, AS, AA, DTR, Certified HIV Counselor is the President of HIV ReSources, Inc., and Editor-In-Chief of the HIV ReSource Review.
 

This two-part article provides information on many complementary therapies that are popular among people living with HIV or AIDS. A summary of information on the use of complementary therapies, herbal regulation, cautionary notes, and selected botanical treatments is in the first portion of the article published in Issue 21. Part Two provides additional information on popular botanical treatments, along with sources for further information, and
highlights the future of dietary supplements.
 Issue 21
This issue is free in PDF
Botanical Use Among People With HIV: Part 1
Nancy Spaulding-Albright RD, CNSD, LD/N
and Sharon Ann Meyer, AA, AS, DTR
Many people living with HIV infection (PLWHIV) consider complementary therapies an important part of treatment and care. The popularity of herbal medications as adjunctive therapy for HIV and AIDS has grown significantly in the past several years. Studies continue to show that PLWHIV and AIDS spend a significant part of their money on complementary treatments such as botanicals and other supplements. One look at the shelves of a local drug or grocery store serves to show that since passage of the 1994 Dietary Supplement and Education Act (DSHEA), the popularity of dietary supplements has skyrocketed. Even major pharmaceutical companies are now participating in this rapidly growing industry. Total sales for dietary supplements in 1998 totaled almost $12 billion and are projected to increase to $14 billion by the year 2000. Retail botanical sales within the U.S. were $1.5 billion in 1995 and industry experts predict that by the year 2000, consumers will be buying more than $5 billion in herbal products.

Considering ongoing research on the benefits of various phytochemicals in our food supply, it is not hard to imagine that the chemical compounds from herbs
could also be helpful in the therapy of HIV disease. Healthcare providers must provide patients with accurate scientific information about these products noting what has promise, what is useless, and what is potentially harmful.

This two-part article provides a summary of botanical use
within the HIV population and offers information on the
future of dietary supplements as of January 2000.

Issue 20: The Role Of Glutamine In HIV
Beth Ellen DiLuglio, MS, RD, CNSD, LD/N
and Sharon Ann Meyer, AA, AS, DTR
Glutamine is the most abundant amino acid in the body. It is a major building block of skeletal muscle, an important fuel for the gastrointestinal (GI) tract, and plays a major role in nitrogen transport. Although made in most tissues, it is synthesized primarily in the skeletal muscle and released into the circulation where it constitutes 60% of the body's free amino acid pool. Glutamine is a 'conditionally essential' amino acid that is vital for the normal function of many body cells and organs. This versatile amino acid plays a part in maintaining acid-base balance in the body; provides precursors for hepatic gluconeogenesis and urea synthesis; and is a precursor to glutathione (GSH), an important antioxidant. It plays a vital role in overall nitrogen metabolism. Using its two atoms of nitrogen, it is able to transport nitrogen between skeletal muscle and visceral organs, picking up and dropping off nitrogen atoms as needed for protein and DNA synthesis. Besides this, glutamine plays a major role in many other physiologic functions, including the provision of energy to rapidly dividing cells such as enterocytes, colonocytes, lymphocytes, macrophages, fibroblasts, and malignant cells. Due to its many attractive properties, glutamine is a popular supplement among people living with HIV infection (PLWHIV). Product distributors note that along with other ingredients, glutamine can increase immune function in humans.

This literature review highlights the use of glutamine in humans and offers information on its role in PLWHIV as of September 1999.

Issue 19
This issue is free in PDF
Does HMB Increase Muscle Size And Strength?
Ellen Coleman, MA, MPH, RD

HMB (beta-hydroxy-beta-methylbutyrate)
By Joseph Cannon, MS, CSCS, NSCA-
Certified Personal Trainer, and
Sharon Ann Meyer, AA, AS, DTR

HMB (ß-hydroxy ß-methylbutyrate) was discovered by research scientists at Iowa State University. The dietary supplement has been touted to increase muscle mass and at the same time decrease body fat. Several investigators document the use of HMB, either alone or mixed with other substances, in animals and humans. Considering the research, it's no surprise that HMB is an ingredient in yet another popular supplement designed for those living with HIV. 

These articles review HMB research (as of July 1999) and
provide useful supplementation advice.

Issue 18: MILK THISTLE: SILYMARIN
By Sharon Ann Meyer, AA, AS, DTR
Silymarin, a polyphenolic antioxidant, is derived from the milk thistle plant. Although people have used milk thistle derivatives for almost 2,000 years their popularity has increased greatly since 1968 when someone discovered its active ingredient. Individuals, including people living with HIV infection, use milk thistle and silymarin for a variety of reasons.

This article reviews the extensive research of milk thistle on
animals and humans as of May 1999.

Issue 17
This issue is free in PDF
A REVIEW OF NITAZOXANIDE
By Sharon Ann Meyer, AA, AS, DTR
AIDS activists often note the seriousness of contamination with Cryptosporidium parvum, a parasite found in the feces of infected humans or animals. It's a life-threatening disease for HIV-positive people occurring each year in an estimated 10- 20% of those who have diarrhea. According to researcher Dr. Rosemary Soave, at the New York Hospital Cornell Medical Center, the disease often results in disturbed sleep patterns, decreased quality of life, dehydration, loss of appetite and subsequent wasting. Many cases of human cryptosporidiosis go unrecognized in people living with HIV. 

Cryptosporidium is mainly localized to the gastrointestinal tract and persistent infection causes watery diarrhea that is very severe and leads to dehydration. Besides the diarrhea, symptoms include stomach cramps, rectal urgency and incontinence, fatigue, diminished appetite, nausea and vomiting, weight loss, or a slight fever. The management of cryptosporidia can include Azithromycin, bismuth subsalicylate, Lomotil, Loperamide, Paromomycin, paregoric,  Octreotide, hyperimmune bovine colostrum or Nitazoxanide (NTZ).

This article reviews the use of NTZ for the treatment of
cryptosporidiosis as of March 1999.
Issue  16
This issue is free in PDF
THINK ABOUT ZINC
By Sharon Ann Meyer, AA, AS, DTR
Zinc and other trace mineral abnormalities are common in HIV-positive men, women and children. Miami researchers know that adequate amounts of dietary zinc are needed to slow the progression of HIV disease. Yet there is much confusion and disagreement as to whether supplements of this trace mineral may help or harm people living with HIV infection (PLWHIV). 

This review of zinc research (as of January 1999) affords the reader with a summary of the issues surrounding zinc supplementation
among HIV-positive people. 

Issue 15
This issue is free in PDF
BEYOND THE BASICS
By Sharon Ann Meyer, AA, AS, DTR
Great strides have been achieved  over the past 15 years in the realm of micronutrient supplementation. Most HIV-savvy clinicians suggest basic multivitamin and mineral supplements for people living with HIV (PLWHIV). Many of these nutrition professionals now suggest a wider variety of supplements to meet the needs of this population group. One of these supplements is alpha lipoic acid (ALA), which is required by both plants and animals. In the U.S., ALA has been introduced as a metabolic antioxidant. Sources note many years of widespread ALA use among PLWHIV as a liver supportive and antioxidant. Buyer's Clubs encourage the use of daily ALA supplementation by saying it helps to protect the liver. 

This review affords the reader a look at the research
on ALA as of November 1998.

Issue 14
This issue is free in PDF
ONE GARLIC OR TWO?
By Sharon Ann Meyer, AA, AS, DTR
 Many people consume garlic as a preventive measure. Some HIV-positive people use it as prophylactic treatment for fungal infections. Garlic purportedly stimulates macrophage activity to kill viruses, bacteria, and yeast. It's touted to boost the immune system and increase T-helper cell activity. Garlic is purported to prevent inflammation, reduce tumor masses, increase phagocytic function and stimulate the immune system.

This review covers in vitro, animal and
human research of garlic as of September 1998.


 
A few words about HIV ReSources Products

The HIV ReSource Review (issues 1-30) and HIV Nutrition Update (issues 30-54) are peer-reviewed publications designed for nutrition professionals and others interested in nutrition and HIV/AIDS.
 

First published on July 1, 1996, the newsletters still provide important, time-saving, HIV-related nutrition information. Feature articles are the result of original research, scientific literature searches, and searches on the World Wide Web. Article information is supplemented by reviewing conference proceedings and expert recommendations.


 
 
 
Editorial Board
 
Senior Editors
Nancy Spaulding Albright, RD, LD, CNSD, LD
Wendy Wittenbrook, MA,RD,LD
Donna Tinnerello, MS, RD, CDN

Web Site Affiliation(s)
 Always Your Choice
 Jennifer's Virtual Faculty

 
In Spirit- Chester Myers, PhD
 
Assistant Editors
Kevin Kelly, RD, LD

Web Site Affiliation(s) 
North Dakota State University

Jason Stevenson, BS, Medical Researcher
Denise Li, BS
 
 
 
Editor-In-Chief
Sharon Ann Meyer, AA, AS, DTR, Certified HIV Counselor About Sharon

Web Site Affiliation(s) 
HIV ReSources Homepage
The Woman's Place
Sharon's Homepage
Dean Allen DeLong's Homepage

 
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